Ataxia

Differential Diagnosis

Acquired 

    Vascular: stroke

    Infection: cerebellitis, EBV, HIV, syphilis, vaccine, CJD, Whipple

    Toxin/drug: alcohol, bismuth, chemotherapy, AED, Li, Hg, 甲苯, 噴漆

    Autoimmune: Paraneoplastic (anti-Hu, Yo, Ma, Ri, Tr, Ta, CV2, Zic1, Zic4)

    Metabolic: hypothyroidism

    Idiopathic: MSA

    Nutrition: vitamin E, B1, B12, gliadin

    Structure: tumor, trauma, superficial siderosis

Hereditary

    ADCA: SCA

    ARCA: Wilson, FA

                AVED, abetalipoproteinemia, Cayman

                Acereoplasminemia, adrenomyeloneuropathy, 

                late-onset Tay-Sachs, Niemann-Pick disease type C, CTX

                CoQ10 deficiency, pyruvate dehydrogenase complex (PDHC) deficiency

                Mitochondrial recessive ataxia syndrome (MIRAS)

                AT, ATLD, AOA1, AOA2, ARSACS, ARCA, EA

    Mitochondrial: MERRF, MELAS, NARP

    X-linked: FXTAS